ω-Conotoxin MVIIA （ω-漏斗網(wǎng)蛛毒素MVIIA）

簡要描述：Smartox Biotechnology是*一家專門生產(chǎn)動物毒液多肽毒素，用于細(xì)胞離子通道功能研究的生物醫(yī)藥公司。多肽毒素在生物制藥領(lǐng)域具有重要的使用價(jià)值。

產(chǎn)品型號：08CON001
廠商性質(zhì)：代理商
更新時(shí)間：2024-10-30
訪問量：1862

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產(chǎn)品介紹

ω-Conotoxin MVIIA / Omega-conotoxin MVIIA(ω-漏斗網(wǎng)蛛毒素MVIIA)

Blocker of N-type voltage-gated calcium channels

N型電壓門控鈣通道阻斷劑

ω-Conotoxin MVIIA (omega-conotoxin MVIIA) has been isolated from the venom of the cone Conus magus. Omega-conotoxins act at presynaptic membranes, they bind and block voltage-sensitive calcium channels (VSCC). ω-conotoxin MVIIA blocks N-type voltage-gated calcium channels (Ca_v2.2/CACNA1B). ω-conotoxin MVIIA is available as analgesic drug under the name Prialt^®. It blocks acute pain in patients who no longer obtain relief from opiate drugs. It is 100 to 1.000 times more potent than morphine. This toxin blocks calcium channels and disables nerves that transmit pain signals.

ω-Conotoxin MVIIA (ω-漏斗網(wǎng)蛛毒素MVIIA)技術(shù)資料

氨基酸序列：

Cys¹-Lys-Gly-Lys-Gly-Ala-Lys-Cys⁸-Ser-Arg-Leu-Met-Tyr-Asp-Cys¹⁵-Cys¹⁶-Thr-Gly-Ser-Cys²⁰-Arg-Ser-Gly-Lys-Cys²⁵-NH₂

二硫鍵：Cys¹-Cys¹⁶, Cys⁸-Cys²⁰ and Cys¹⁵-Cys²⁵

長度 (aa)：25

分子式：C₁₀₂H₁₇₂N₃₆O₃₂S₇

分子量： 2639.18 Da

外觀：White lyophilized solid

可溶性： water and saline buffer

CAS 號： [107452-89-1]

來源：Synthetic

純度：> 97 %

產(chǎn)品信息

08CON001-00100	ω-Conotoxin MVIIA(ω-漏斗網(wǎng)蛛毒素MVIIA)	0.1mg
08CON001-00500	ω-Conotoxin MVIIA(ω-漏斗網(wǎng)蛛毒素MVIIA)	0.5mg
08CON001-01000	ω-Conotoxin MVIIA(ω-漏斗網(wǎng)蛛毒素MVIIA)	1mg